BDBM549540 US11306071, Compound 116::US11306071, Compound 121

SMILES C[C@H](NC(=O)c1nc(-c2cc(Cl)c3ncccc3c2)c(nc1N)-c1ccccc1)c1cccc(n1)C#N

InChI Key InChIKey=NVUXJKIYOBBZKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549540   

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549540(US11306071, Compound 116 | US11306071, Compound 12...)
Affinity DataIC50: 5.40nMAssay Description:The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549540(US11306071, Compound 116 | US11306071, Compound 12...)
Affinity DataIC50: 1.10nMAssay Description:The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent