BDBM549410 2-{4-[(1S)-1-[(4-chloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2- hydroxyethyl]benzenesulfonyl}acetic acid::US11304929, Example 03-002
SMILES Cc1cc(Cl)c2cc(C(=O)N[C@H](CO)c3ccc(cc3)S(=O)(=O)CC(O)=O)n(C)c2c1
InChI Key InChIKey=IRYAJNZVJASVSQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 549410
Affinity DataIC50: 6nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibition of PHGDH (unknown origin) preincubated for 30 mins followed by substrate addition and measured after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of wild type PHGDH (unknown origin) preincubated for 30 mins followed by substrate addition and measured after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PHGDH D175A mutant (unknown origin) preincubated for 30 mins followed by substrate addition and measured after 5 minsMore data for this Ligand-Target Pair