BDBM549388 2-{4-[(1R)-1-[(4-chloro-1,6,7-trimethyl-1H-indol-2- yl)formamido]ethyl]benzenesulfonyl}acetic acid::US11304929, Example 03-003

SMILES C[C@@H](NC(=O)c1cc2c(Cl)cc(C)c(C)c2n1C)c1ccc(cc1)S(=O)(=O)CC(O)=O

InChI Key InChIKey=VLLASYGOTZYGLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549388   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM549388(2-{4-[(1R)-1-[(4-chloro-1,6,7-trimethyl-1H-indol-2...)
Affinity DataIC50: 13nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM549388(2-{4-[(1R)-1-[(4-chloro-1,6,7-trimethyl-1H-indol-2...)
Affinity DataIC50: 22nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent