BDBM549374 2-{4-[(1S)-1-[(4,5-difluoro-1,6-dimethyl-1H-indol-2-yl)formamido]-2- hydroxyethyl]benzenesulfonyl}acetic acid::US11304929, Example 03-012

SMILES Cc1cc2n(C)c(cc2c(F)c1F)C(=O)N[C@H](CO)c1ccc(cc1)S(=O)(=O)CC(O)=O

InChI Key InChIKey=MESJYZUFOOMTIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549374   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM549374(2-{4-[(1S)-1-[(4,5-difluoro-1,6-dimethyl-1H-indol-...)
Affinity DataIC50: 8nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM549374(2-{4-[(1S)-1-[(4,5-difluoro-1,6-dimethyl-1H-indol-...)
Affinity DataIC50: 17nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent