BDBM549304 2-chloro-N-(3- methoxyphenyl)-5- oxido-6,7-dihydro- thieno[3,2-d]pyrimi- din-5-ium-4-amine::US11299497, Example 19

SMILES CCNc1nc(nc2CC[S@@+]([O-])c12)N(C)CCC1CCOCC1

InChI Key InChIKey=DABQWESBOTZJEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549304   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandPNGBDBM549304(2-chloro-N-(3- methoxyphenyl)-5- oxido-6,7-dihydro...)
Affinity DataIC50: 100nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
Go to US Patent