BDBM549301 2-chloro-N-[(1R)-1- methylpropyl]-5- oxido-6,7-dihydro- thieno[3,2-d]pyrimi- din-5-ium-4-amine::US11299497, Example 16

SMILES COc1cccc(Nc2nc(nc3CC[S@@+]([O-])c23)N(C)CCC2CCOCC2)c1

InChI Key InChIKey=QTAYTESMHCRJFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549301   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandPNGBDBM549301(2-chloro-N-[(1R)-1- methylpropyl]-5- oxido-6,7-dih...)
Affinity DataIC50: 10nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
Go to US Patent