BDBM549191 US11299493, Compound 1.16::US11299493, S-16

SMILES CCn1n(-c2cccc(n2)C(C)(C)O)c2nc(Nc3ccc4c(CN(C)CC4(C)C)c3)ncc2c1=O

InChI Key InChIKey=SITDKOBSGOYIKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549191   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549191(US11299493, S-16 | US11299493, Compound 1.16)
Affinity DataIC50: 4.5nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent