BDBM549086 BDBM50556920::US11299480, Example 117

SMILES ONC(=O)c1ccc(N(Cc2ccc(cn2)C2CCCCC2)C(=O)[C@H]2CCN2S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c(F)c1

InChI Key InChIKey=NZBRGIKWMCBHTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549086   

TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM549086(BDBM50556920 | US11299480, Example 117)
Affinity DataIC50: 890nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain (unknown origin) preincubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM549086(BDBM50556920 | US11299480, Example 117)
Affinity DataIC50: 889nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2022
Entry Details
Go to US Patent