BDBM548779 WO2022098806, Compound 2-40

SMILES COc1cc2CCN(C)Cc2cc1Nc1ncc2c(N)cc(cc2n1)-c1cnc2OCCNc2c1C

InChI Key InChIKey=FCHXKYDDXPTBDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 548779   

LigandPNGBDBM548779(WO2022098806, Compound 2-40)
Affinity DataIC50: 0.630nMAssay Description: To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2022
Entry Details
WIPO WO2022098806

LigandPNGBDBM548779(WO2022098806, Compound 2-40)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of HPK1 (unknown origin) using myelin basic protein as substrate incubated for 60 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed