BDBM547719 US11292792, CMPD # I-49

SMILES O=C1CCC(C(=O)N1)n1c2ccccc2c2c(ccnc12)C#CCOCCOCCOCc1ccccc1

InChI Key InChIKey=YWYPFSNXEQBNQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547719   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM547719(US11292792, CMPD # I-49)
Affinity DataIC50: 10nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
Go to US Patent