BDBM54572 1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-pentanone::1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pentan-1-one::1-[4-(2,5-dimethylphenyl)piperazino]-5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pentan-1-one::KUC103399N::UNM-0000306116::cid_42628042

SMILES COc1ccc(cc1)-c1noc(CCCCC(=O)N2CCN(CC2)c2cc(C)ccc2C)n1

InChI Key InChIKey=IWNOKPGNWFUZEG-UHFFFAOYSA-N

Data  3 KI  2 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 54572   

LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  1.16E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetGTPase KRas [1-37](Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  2.10E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetRas-related protein Rab-7a(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetRas-related protein Rab-2A(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetGTPase KRas [1-37](Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataEC50:  1.74E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details
PCBioAssay
TargetZinc finger protein GLI1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataIC50: 4.00E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetProtein Wnt-3a(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataIC50: 2.84E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataKi:  1.06E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataKi:  1.96E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandPNGBDBM54572(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-5-[3-(4-m...)
Affinity DataKi:  2.69E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay