BDBM5452 6-alkoxy-4-anilinoquinazoline 10a::N-[4-(benzyloxy)phenyl]-6-(prop-2-en-1-yloxy)quinazolin-4-amine

SMILES C=CCOc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1

InChI Key InChIKey=PNZSTSKDYDRMIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5452   

TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandPNGBDBM5452(N-[4-(benzyloxy)phenyl]-6-(prop-2-en-1-yloxy)quina...)
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandPNGBDBM5452(N-[4-(benzyloxy)phenyl]-6-(prop-2-en-1-yloxy)quina...)
Affinity DataIC50: 347nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed