BDBM544456 (2S)-3-[3-[3-[(2S)-2-Carboxy-2-[(3R)-pyrrolidin-3-yl]ethyl]anilino]phenyl]-2-[(3R)-pyrrolidin-3-yl]propanoic acid; dihydrochloride::US11286249, Example 14

SMILES OC(=O)[C@@H](Cc1cccc(Nc2cccc(C[C@@H]([C@H]3CCNC3)C(O)=O)c2)c1)C1CCNC1

InChI Key InChIKey=QFOIJIXXQTZZTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 544456   

TargetApolipoprotein(a)(Human)
Eli Lilly

US Patent
LigandPNGBDBM544456((2S)-3-[3-[3-[(2S)-2-Carboxy-2-[(3R)-pyrrolidin-3-...)
Affinity DataIC50: 0.314nMAssay Description:The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
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