BDBM54366 (6E)-3-benzoxy-6-[4-(4-methoxyphenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[4-(4-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-phenylmethoxy-1-cyclohexa-2,4-dienone::(6E)-6-[4-(4-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-phenylmethoxy-cyclohexa-2,4-dien-1-one::(6E)-6-[4-(4-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-phenylmethoxycyclohexa-2,4-dien-1-one::5-Benzyloxy-2-[4-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-phenol::MLS000778889::SMR000415582::cid_16681768

SMILES COc1ccc(cc1)-c1c[nH]nc1-c1ccc(OCc2ccccc2)cc1O

InChI Key InChIKey=BWESOJDUGFHHBI-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 54366   

TargetTumor necrosis factor(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54366(SMR000415582 | (6E)-6-[4-(4-methoxyphenyl)-1,2-dih...)
Affinity DataIC50: 1.84E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54366(SMR000415582 | (6E)-6-[4-(4-methoxyphenyl)-1,2-dih...)
Affinity DataIC50: 3.21E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54366(SMR000415582 | (6E)-6-[4-(4-methoxyphenyl)-1,2-dih...)
Affinity DataEC50:  1.22E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54366(SMR000415582 | (6E)-6-[4-(4-methoxyphenyl)-1,2-dih...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay