BDBM543427 US11279697, Compound 292-P1

SMILES COc1cc(OC)c(Cl)c([C@@H]2CCc3c(C2)[nH]nc3-c2cc(F)ccc2NC(=O)C=C)c1Cl

InChI Key InChIKey=JCFANGBRJYEZOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 543427   

TargetFibroblast growth factor receptor 4(Human)
Bioardis

US Patent
LigandPNGBDBM543427(US11279697, Compound 292-P1)
Affinity DataIC50: 132nMAssay Description:A HTRF KinEASE-TK 20000 tests kinase assay kit from CISBIO Corp. was used. The kit provided a biotin-labeled substrate, an EU-labeled phosphorylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 4(Human)
Bioardis

US Patent
LigandPNGBDBM543427(US11279697, Compound 292-P1)
Affinity DataIC50: 135nMAssay Description:A HTRF KinEASE-TK 20000 tests kinase assay kit from CISBIO Corp. was used. The kit provided a biotin-labeled substrate, an EU-labeled phosphorylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 4(Human)
Bioardis

US Patent
LigandPNGBDBM543427(US11279697, Compound 292-P1)
Affinity DataIC50: 135nMAssay Description:A HTRF KinEASE-TK 20000 tests kinase assay kit from CISBIO Corp. was used. The kit provided a biotin-labeled substrate, an EU-labeled phosphorylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
Go to US Patent