BDBM543076 3-(4-{methyl[(1S)-1- phenylethyl]sulfamoyl}phenyl)-1-(pyridin-3- ylmethyl)urea::US11279687, Compound 85

SMILES C[C@H](N(C)S(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1)c1ccccc1

InChI Key InChIKey=XGNUYELTSDLMKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543076   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM543076(3-(4-{methyl[(1S)-1- phenylethyl]sulfamoyl}phenyl)...)
Affinity DataIC50: 1nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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