BDBM541996 US11273153, Compound 4.1

SMILES OCCC#Cc1sc(c(c1CCCc1ccccc1)-c1ccncc1)-c1ccc(F)cc1

InChI Key InChIKey=MWZFTZVHSSDOOT-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 541996   

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM541996(US11273153, Compound 4.1)
Affinity DataIC50: 180nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM541996(US11273153, Compound 4.1)
Affinity DataIC50: 180nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM541996(US11273153, Compound 4.1)
Affinity DataKi:  600nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM541996(US11273153, Compound 4.1)
Affinity DataKi:  600nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM541996(US11273153, Compound 4.1)
Affinity DataKi:  2.30E+3nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM541996(US11273153, Compound 4.1)
Affinity DataKi:  2.30E+3nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent