BDBM541669 US11267811, Example 311

SMILES Cc1nnc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n1-c1cc(Cl)ccc1C(F)(F)F

InChI Key InChIKey=JRURYEFDCGQBFQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 541669   

TargetGalectin-3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541669(US11267811, Example 311)
Affinity DataIC50: 12nMAssay Description:The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
Go to US Patent

TargetGalectin-3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541669(US11267811, Example 311)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541669(US11267811, Example 311)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541669(US11267811, Example 311)
Affinity DataIC50: 67nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541669(US11267811, Example 311)
Affinity DataIC50: 7.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541669(US11267811, Example 311)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGalectin-9(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541669(US11267811, Example 311)
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed