BDBM540686 (2R,4S)-4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)-3-oxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl)-1-(2-2-methoxyethyl)pyrrolidine-2-carboxylic Acid::US11261190, Example 7

SMILES COCCN1C[C@H](C[C@@H]1C(O)=O)N1C[C@@H]2CN(CC3=C([C@@H](N=C(N3)c3nccs3)c3ccc(F)cc3Cl)C(=O)OC)CCN2C1=O

InChI Key InChIKey=MOEQWRQYVHQDSJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540686   

TargetLarge envelope protein(HBV-D)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM540686((2R,4S)-4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)...)
Affinity DataEC50:  56nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent