BDBM540048 US11261183, Example 51::US11261183, Example 52::US11261183, Example 53::US11261183, Example 54

SMILES CC(N1CCN(CC1)c1ncc(cn1)S(C)(=N)=O)c1ccc2sc(C)nc2c1

InChI Key InChIKey=RFNJEAKSVBJKCL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 540048   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM540048(US11261183, Example 52 | US11261183, Example 53 | ...)
Affinity DataIC50: 50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM540048(US11261183, Example 52 | US11261183, Example 53 | ...)
Affinity DataIC50: 600nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM540048(US11261183, Example 52 | US11261183, Example 53 | ...)
Affinity DataIC50: 50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM540048(US11261183, Example 52 | US11261183, Example 53 | ...)
Affinity DataIC50: 5.50E+3nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent