BDBM539876 2-chloro-4-(difluoro- methyl)benzene-1- sulfonyl chloride::US11260049, Ex. 14::US11260049, Ex. 22

SMILES FC(F)c1ccc(c(Cl)c1)S(Cl)(=O)=O

InChI Key InChIKey=LJNVMQCREBXXKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 539876   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline Intellectual Property (No. 2)

US Patent
LigandPNGBDBM539876(2-chloro-4-(difluoro- methyl)benzene-1- sulfonyl c...)
Affinity DataIC50: 5nMAssay Description:TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline Intellectual Property (No. 2)

US Patent
LigandPNGBDBM539876(2-chloro-4-(difluoro- methyl)benzene-1- sulfonyl c...)
Affinity DataIC50: 55nMAssay Description:TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent