BDBM539231 (2S,3S,4R,5R)-2-((R)-7-chloro- 1,5- dihydrobenzo[e][1,3]dioxepin-1- yl)-5-(4-methyl-7H-pyrrolo[2,3- d]pyrimidin-7- yl)tetrahydrofuran-3,4-diol::US11254683, Example 55

SMILES Cc1cnnc2n(ccc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)[C@@H]1OCOCc2cc(Cl)ccc12

InChI Key InChIKey=WMBBADXVRALADZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539231   

TargetProtein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM539231((2S,3S,4R,5R)-2-((R)-7-chloro- 1,5- dihydrobenzo[...)
Affinity DataIC50: 11.7nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent