BDBM538245 US11254663, Example 71

SMILES O=C(C1CCC1)N(CC12CCC(CC1)(CC2)c1nc(CC2CC2)no1)c1cccc(c1)-c1nc(no1)C1CC1

InChI Key InChIKey=ITYGTXZCGHBICI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 538245   

TargetBile acid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM538245(US11254663, Example 71)
Affinity DataEC50:  406nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2022
Entry Details
Go to US Patent