BDBM537939 US11248001, Example 468

SMILES O=c1cccnn1-c1ccc(N[C@H]2CC[C@@H](C2)Nc2ncc(cn2)C2CC2)nc1

InChI Key InChIKey=FECDSEUAOKXYDM-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 537939   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537939(US11248001, Example 468)
Affinity DataKd: <200nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CMS (GE Hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537939(US11248001, Example 468)
Affinity DataKd: <200nMAssay Description:Inhibition of human recombinant Avi-tagged PCSK9 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed