BDBM537740 US11248001, Example 90::US11603523, Example 90

SMILES CSc1cnc(NCC(C)CNc2nc3ccc(cc3s2)S(=O)(=O)N2CCNCC2)nc1

InChI Key InChIKey=BDRZWMHQYGYPCU-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 537740   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537740(US11248001, Example 90 | US11603523, Example 90)
Affinity DataKd: <200nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CM5 (GE Hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537740(US11248001, Example 90 | US11603523, Example 90)
Affinity DataKd: <200nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CMS (GE Hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent