BDBM537024 (E)-3-(2-((4-((S)-2-(4-chlorophenyl)benzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-imidazol-5-yl)-2-methylacrylic acid (Compound 133a) and (E)-3-(2-((4-((R)-2-(4-chlorophenyl)benzo[d][1,3]dioxol-4-yl) piperidin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-imidazol-5-yl)-2-methylacrylic acid ::US11897851, Compound 133b

SMILES C\C(=C/c1cnc(CN2CCC(CC2)c2cccc3O[C@H](Oc23)c2ccc(Cl)cc2)n1C[C@@H]1CCO1)C(O)=O

InChI Key InChIKey=UMAUTEIQRLDITR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537024   

TargetGlucagon-like peptide 1 receptor(Human)
Gasherbrum Bio

US Patent
LigandPNGBDBM537024((E)-3-(2-((4-((S)-2-(4-chlorophenyl)benzo[d][1,3]d...)
Affinity DataEC50:  48nMAssay Description:To optimize functional activity directed toward Gas coupling, a HEK293/CRE-Luc cell line developed by HDB stably expressing the GLP-1 Receptor was us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
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