BDBM537022 (E)-3-(2-((4-(2-(4-chloro-2-fluorophenyl)benzol[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-((S)-oxetan-2-ylmethyl)-1H-imidazol-5-yl)-2-methylacrylic acid ::US11897851, Compound 132a

SMILES C\C(=C/c1cnc(CN2CCC(CC2)c2cccc3OC(Oc23)c2ccc(Cl)cc2F)n1C[C@@H]1CCO1)C(O)=O

InChI Key InChIKey=XCVHKEDFGKKZRE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537022   

TargetGlucagon-like peptide 1 receptor(Human)
Gasherbrum Bio

US Patent
LigandPNGBDBM537022((E)-3-(2-((4-(2-(4-chloro-2-fluorophenyl)benzol[d]...)
Affinity DataEC50:  1.60nMAssay Description:To optimize functional activity directed toward Gas coupling, a HEK293/CRE-Luc cell line developed by HDB stably expressing the GLP-1 Receptor was us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
Go to US Patent