BDBM536995 (E)-3-(5-((4-(6-((4-chloro-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-4-methyl-4H-1,2,4-triazol-3-yl)acrylic acid ::US11897851, Compound 112

SMILES Cn1c(CN2CCC(CC2)c2cccc(OCc3ccc(Cl)cc3F)n2)nnc1\C=C\C(O)=O

InChI Key InChIKey=IBZOAQMRMLNAHC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536995   

TargetGlucagon-like peptide 1 receptor(Human)
Gasherbrum Bio

US Patent
LigandPNGBDBM536995((E)-3-(5-((4-(6-((4-chloro-2-fluorobenzyl)oxy)pyri...)
Affinity DataEC50:  2.01nMAssay Description:To optimize functional activity directed toward Gas coupling, a HEK293/CRE-Luc cell line developed by HDB stably expressing the GLP-1 Receptor was us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
Go to US Patent