BDBM5366 1-phenyl-5-{6-[2-(piperidin-1-yl)ethoxy]pyridin-3-yl}-1H-1,3-benzodiazole::benzimidazole deriv. 5

SMILES C(CN1CCCCC1)Oc1ccc(cn1)-c1ccc2n(cnc2c1)-c1ccccc1

InChI Key InChIKey=VXZJDAXLBCMRRZ-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5366   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5366(1-phenyl-5-{6-[2-(piperidin-1-yl)ethoxy]pyridin-3-...)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed