BDBM536512 (S)-5-(1-(2-((3-chloro- 6-(2,4-dimethylpipera- zin-1-yl)-2-fluoro- pyridin-4-yl)amino)-2- oxoethyl)-4-oxo-4,6,7,8- tetrahydro-1H-dipyrrolo [1,2-a:2',3'-d]pyrimidin- 3-yl)-3-fluoro-2- hydroxy-4-methoxy- benzamide::US11242351, Compound I-91

SMILES COc1c(F)c(O)c(cc1-c1cn(CC(=O)Nc2cc(nc(F)c2Cl)N2CCN(C)C[C@@H]2C)c2nc3CCCn3c(=O)c12)C(N)=O

InChI Key InChIKey=PJXHIWAHCJGLOV-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536512   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536512((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethylpipera- zin...)
Affinity DataKd:  94.7nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent