BDBM536451 5-(1-(2-((2-chloro-4- fluoro-5-morpholino- phenyl)amino)-2-oxo- ethyl)-4-oxo-4,6,7,8- tetrahydro-1H-dipyrrolo [1,2-a:2',3'-d]pyrimidin- 3-yl)-3,4-difluoro-2- hydroxybenzamide::US11242351, Compound I-30

SMILES NC(=O)c1cc(-c2cn(CC(=O)Nc3cc(N4CCOCC4)c(F)cc3Cl)c3nc4CCCn4c(=O)c23)c(F)c(F)c1O

InChI Key InChIKey=LHPSCRKAXVEHHI-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536451   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536451(5-(1-(2-((2-chloro-4- fluoro-5-morpholino- phenyl)...)
Affinity DataKd:  106nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent