BDBM536446 (S)-5-(1-(2-((3-chloro-2- fluoro-6-(4-(2- methoxyethyl)-2-methyl- piperazin-1-yl)pyridin-4- yl)amino)-2-oxoethyl)-4- oxo-4,6,7,8-tetrahydro- 1H-dipyrrolo[1,2-a:2',3'- d]pyrimidin-3-yl)-3,4- difluoro-2-hydroxy- benzamide::US11242351, Compound I-25

SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1

InChI Key InChIKey=PLSOXLGFMFFJOA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536446   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536446((S)-5-(1-(2-((3-chloro-2- fluoro-6-(4-(2- methoxye...)
Affinity DataKd:  5.64nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent