BDBM536437 (S)-5-(1-(2-((3-chloro- 2-fluoro-6-(3-methyl- morpholino)pyridin-4- yl)amino)-2oxoethyl)- 4-oxo-4,6,7,8-tetra- hydro-1H-dipyrrolo [1,2-a:2',3'-d]pyri- midin-3-yl)-4-fluoro- 2-hydroxy-3-methoxy- benzamide::US11242351, Compound I-16

SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(nc(F)c3Cl)N3CCOC[C@@H]3C)c3nc4CCCn4c(=O)c23)c1F)C(N)=O

InChI Key InChIKey=NDWFNJHGTAKMAN-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536437   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536437((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(3-methyl- morp...)
Affinity DataKd:  34.2nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent