BDBM536427 (S)-5-(1-(2-((5-chloro-2- (4-(cyclopropylmethyl)- 2-methylpiperazin-1-yl) pyridin-4-yl)amino)-2- oxoethyl)-4-oxo- 4,6,7,8-tetrahydro-1H- dipyrrolo[1,2-a:2',3'- d]pyrimidin-3-yl)-3,4- difluoro-2-hydroxy- benzamide::US11242351, Compound I-6

SMILES C[C@H]1CN(CC2CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1

InChI Key InChIKey=RDYVQQQGXZAAGJ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536427   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536427((S)-5-(1-(2-((5-chloro-2- (4-(cyclopropylmethyl)- ...)
Affinity DataKd:  25.9nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent