BDBM536342 6-((2-ethyl-4'-(1,1,1,3,3,3- hexafluoro-2-hydroxypropan-2-yl)- 2'-methyl-[1,1'-biphenyl]-4- yl)methyl)-2-thia-6- azaspiro[3.3]heptane 2,2-dioxide::US11242350, Example 18

SMILES CCc1cc(CN2CC3(C2)CS(=O)(=O)C3)ccc1-c1ccc(cc1C)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=HULKIMPPUJRROJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536342   

TargetNuclear receptor ROR-gamma(Human)
Escalier Biosciences

US Patent
LigandPNGBDBM536342(6-((2-ethyl-4'-(1,1,1,3,3,3- hexafluoro-2-hydroxyp...)
Affinity DataIC50: 50nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent