BDBM536337 1,1,1,3,3,3-hexafluoro-2-(2'-fluoro- 6'-isopropyl-4'-((6-(methylsulfonyl)- 2,6-diazaspiro[3.3]heptan-2- yl)methyl)-[1,1'-biphenyl]-4- yl)propan-2-ol::US11242350, Example 15

SMILES CC(C)c1cc(CN2CC3(C2)CN(C3)S(C)(=O)=O)cc(F)c1-c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ISNQJOKZEPFGIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536337   

TargetNuclear receptor ROR-gamma(Human)
Escalier Biosciences

US Patent
LigandPNGBDBM536337(1,1,1,3,3,3-hexafluoro-2-(2'-fluoro- 6'-isopropyl-...)
Affinity DataIC50: 50nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
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Date in BDB:
6/10/2022
Entry Details
US Patent