BDBM536321 US11242350, Example 2::US11242350, Example 56::US11242350, Example 59

SMILES CCc1cc(CN2CC3(C2)CN(C3)S(C)(=O)=O)ccc1-c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=BDVDLIHHBKNGDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 536321   

TargetNuclear receptor ROR-gamma(Human)
Escalier Biosciences

US Patent
LigandPNGBDBM536321(US11242350, Example 59 | US11242350, Example 56 | ...)
Affinity DataIC50: 50nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Escalier Biosciences

US Patent
LigandPNGBDBM536321(US11242350, Example 59 | US11242350, Example 56 | ...)
Affinity DataIC50: 150nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Escalier Biosciences

US Patent
LigandPNGBDBM536321(US11242350, Example 59 | US11242350, Example 56 | ...)
Affinity DataIC50: 150nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent