BDBM536314 (E)-2-(2-ethoxy-5-((4-(3-hydroxypropyl)piperazin-1-yl)sulfonyl)phenyl)-5-methyl-4-oxo-7-propyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carbaldehyde oxime::US11242347, Compound 1an::US11897890, Compound lan::US12351585, Compound 1an

SMILES CCCc1c(\C=N\O)c(C)c2n1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(CCCO)CC1

InChI Key InChIKey=RTYJPTPUUQMEAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 536314   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536314((E)-2-(2-ethoxy-5-((4-(3-hydroxypropyl)piperazin-1...)
Affinity DataIC50: 0.420nMAssay Description:Experimental protocol: The test compound, i.e the compound of the present invention, reference compound or water (control) are added to a buffer cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
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TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536314((E)-2-(2-ethoxy-5-((4-(3-hydroxypropyl)piperazin-1...)
Affinity DataIC50: 4.20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536314((E)-2-(2-ethoxy-5-((4-(3-hydroxypropyl)piperazin-1...)
Affinity DataIC50: 0.420nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
Go to US Patent