BDBM536176 US11242344, Example 101.4

SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@@H]1C1=NC(=O)[C@](C)(N1)c1ccc(Br)cc1)C(C)(C)C

InChI Key InChIKey=BXQUIQWJTNLTHH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536176   

LigandPNGBDBM536176(US11242344, Example 101.4)
Affinity DataIC50: 1.08E+5nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
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LigandPNGBDBM536176(US11242344, Example 101.4)
Affinity DataKd:  2.67E+4nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent