BDBM535872 US11241428, Example 17

SMILES Nc1ccc(nc1NC(=O)c1cnc(NC2CC2)nc1)-c1ccc(F)cc1

InChI Key InChIKey=STMDVAPHVHSTPD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 535872   

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent