BDBM535777 (3R)-3-(4-chlorophenyl)-2-[(5- chloropyrimidin-2-yl)methyl]-4-fluoro- 6-[1-(4-fluorooxan-4-yl)-1- hydroxyethyl]-3-[(3S)-oxolan-3-yloxy]- 2,3-dihydro-1H-isoindol-1-one::US11236047, Example 493::US11236047, Example 494::US11236047, Example 516::US20230338337, Compound 494
SMILES CC(O)(c1cc2C(=O)N(Cc3ncc(Cl)cn3)[C@](O[C@H]3CCOC3)(c2c(F)c1)c1ccc(Cl)cc1)C1(F)CCOCC1
InChI Key InChIKey=YHOMQLQCVYYRQC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 535777
Affinity DataIC50: 0.540nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair