BDBM535710 4-(Azetidin-3-ylsulfonyl)-N-(2-(4,4- difluoropiperidin-1-yl)-6- methylpyrimidin-4-yl)-2-(6- azaspiro[2.5]octan-6-yl)benzamide::US11236069, Example 21

SMILES Cc1cc(NC(=O)c2ccc(cc2N2CCC3(CC3)CC2)S(=O)(=O)C2CNC2)nc(n1)N1CCC(F)(F)CC1

InChI Key InChIKey=LKHOUJQGFABPOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535710   

TargetKinesin-like protein KIF18A [1-467](Human)
Amgen

US Patent
LigandPNGBDBM535710(4-(Azetidin-3-ylsulfonyl)-N-(2-(4,4- difluoropiper...)
Affinity DataIC50: 40nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
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