BDBM535705 4-(Cyclopropanesulfonimidoyl)- N-(2-(4,4-difluoropiperidin- 1-yl)pyridin-4-yl)-2-(6- azaspiro[2.5]octan-6- yl)benzamide::US11236069, Example 19-6

SMILES FC1(F)CCN(CC1)c1cc(NC(=O)c2ccc(cc2N2CCC3(CC3)CC2)S(=N)(=O)C2CC2)ccn1

InChI Key InChIKey=KJWQBZQFKFLHOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535705   

TargetKinesin-like protein KIF18A [1-467](Human)
Amgen

US Patent
LigandPNGBDBM535705(4-(Cyclopropanesulfonimidoyl)- N-(2-(4,4-difluorop...)
Affinity DataIC50: 42nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
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