BDBM535652 N-(2-(4,4-Difluoropiperidin-1- yl)-3-fluoropyridin-4-yl)-4((2- hydroxyethyl)sulfonamido)-2- (6-azaspiro[2.5]octan-6- yl)benzamide::US11236069, Example 11-63

SMILES OCCS(=O)(=O)Nc1ccc(C(=O)Nc2ccnc(N3CCC(F)(F)CC3)c2F)c(c1)N1CCC2(CC2)CC1

InChI Key InChIKey=BYEDEDCFUHVPJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535652   

TargetKinesin-like protein KIF18A [1-467](Human)
Amgen

US Patent
LigandPNGBDBM535652(N-(2-(4,4-Difluoropiperidin-1- yl)-3-fluoropyridin...)
Affinity DataIC50: 22nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
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