BDBM535461 6-{[(1R)-1-(4-chlorophenyl)-7-fluoro- 5-(2-hydroxybutan-2-yl)-1-{[1- (hydroxymethyl)cyclopropyl]methoxy}- 3-oxo-2,3-dihydro-1H-isoindol-2- yl]methyl}pyridine-3-carbonitrile::US11236047, Example 410::US11236047, Example 411::US20230338337, Compound 411
SMILES CCC(C)(O)c1cc2C(=O)N(Cc3ccc(cn3)C#N)[C@](OCC3(CO)CC3)(c2c(F)c1)c1ccc(Cl)cc1
InChI Key InChIKey=LCMLWYJDMGQUES-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 535461
Affinity DataIC50: 2.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair