BDBM535401 US11236047, Example 180

SMILES CCn1cc(cn1)C(C)(O)c1cc2C(=O)N(Cc3ccc(Cl)cn3)[C@](OCC3(CC3)C(N)=O)(c2c(F)c1)c1ccc(Cl)cc1

InChI Key InChIKey=DCAVGHLCTQJYEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535401   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM535401(US11236047, Example 180)
Affinity DataIC50: 0.950nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent