BDBM534921 N′-cyano-1-(4-cyanophenyl)-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-methanesulfonimidamide::US11236045, Example 66

SMILES O=C(Nc1c2CCCc2cc2CCCc12)NS(=O)(Cc1ccc(cc1)C#N)=NC#N

InChI Key InChIKey=KGXRPCMKKPWROL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534921   

TargetUromodulin(Human)
Cadila Healthcare

US Patent
LigandPNGBDBM534921(N′-cyano-1-(4-cyanophenyl)-N-((1,2,3,5,6,7-h...)
Affinity DataIC50: 4nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
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