BDBM534907 US11236045, Example 43

SMILES OC(c1cccc(c1)S(=O)(NC(=O)Nc1c2CCCc2cc2CCCc12)=NC#N)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=MRWGMPHNOASUCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534907   

TargetUromodulin(Human)
Cadila Healthcare

US Patent
LigandPNGBDBM534907(US11236045, Example 43)
Affinity DataIC50: 27nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent