BDBM534895 4-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazin-1-yl]-2-(1- methyl-1H-pyrazol-4-yl)-6-[3- (trifluoromethyl)azetidin-1- yl]pyrimidine-5-carbonitrile::US11230547, Compound 6-23

SMILES C[C@@H]1CN(CCN1C(=O)C1CC1)c1nc(nc(N2CC(C2)C(F)(F)F)c1C#N)-c1cnn(C)c1

InChI Key InChIKey=GSAAFQPAICRCFQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534895   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534895(4-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazi...)Copy SMILESCopy InChI

Affinity DataIC50: 83nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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