BDBM534884 2-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazin-1-yl]-4-(2- methoxyethyl)-6-(1-methyl- 1H-pyrazol-4-yl)pyrimidine-5- carbonitrile::US11230547, Compound 6-12

SMILES COCCc1nc(nc(-c2cnn(C)c2)c1C#N)N1CCN([C@H](C)C1)C(=O)C1CC1

InChI Key InChIKey=KWTOQOGGHJNQQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534884   

LigandPNGBDBM534884(2-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazi...)
Affinity DataIC50: 58nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
US Patent